P. carinii pneumonia (PCP)- Child, adult: 3-4 mg/kg IV, IM once qd × 14-21 day. Or, in child, 150 mg/m2 qd × 5 day, then 100 mg/m2 for rest of treatment.
Prophylaxis of PCP- Child, adult: 300 mg by inhalant, inhalation with Respirgard II jet nebulizer once q 4 wk.
Prophylaxis of Trypanosoma gambiense- Child, adult: 4 mg/kg IV, IM q 3-6 month.
Leishmaniasis- Child, adult: 2-4 mg/kg IV or IM qd or every other qd, up to 15 doses. |